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Role of Quantitative Wall Motion Analysis In Patients with Acute Chest Pain at Emergency Department
Kyung-Hee Kim2, Sang Hoon Na1*, Jin-Sik Park2
1Seoul National University Hospital Internal Medicine, Cardiology
2Sejong General Hospital, Internal medicine, Cardiology
Corresponding Author: Sang Hoon Na ,Email:
Evaluation of acute chest pain in emergency department (ED), using limited resource and time, is still very difficult despite recent development of many diagnostic tools. In this study, we tried to determined the applicability of new semi-automated cardiac function analysis tool, Velocity vector imaging (VVI), in the evaluation of the patients with acute chest pain in ED. Method: We prospectively enrolled 48 patients, who visited ED with acute chest pain, and store images to analyze VVI from July 2005 to July 2007.
In 677 (88%) of 768 segments the analysis by VVI was feasible among 48 patients. Peak systolic radial velocity (Vpeak) and strain significantly decreased according to visual regional wall motion abnormality (Vpeak, 3.50±1.34 cm/s for normal vs 3.46±1.52 cm/s for hypokinesia, 2.51±1.26 for akinesia, p < 0.01; Peak systolic radial strain -31.74±9.15% for normal, -24.33±6.28% for hypokinesia, -20.30±7.78% for akinesia, p< 0.01). However, the velocity vectors at the time of MVO were directed outward in the visually normal myocardium, inward velocity vectors were revealed in the visually akinetic area (VMVO, -0.85±1.65cm/s for normal vs 0.10±1.46 cm/s for akinesia, p < 0.001). At coronary angiography, VMVO clearly increased in the ischemic area (VMVO, -0.88+1.56cm/s for normal vs 0.70+2.04cm/s for ischemic area, p <0.01).
Regional wall motion assessment using VVI showed could be used to detect significant ischemia in the patient with acute chest pain at ED.
Keywords: Velocity vector imaging, Quantitative wall motion analysis, Chest pain, Emergency department
Volume 26, No 1
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