Advanced Search
| Home | Sitemap | Contact us
Table of Contents
PDF Links PDF Links
Systematic left ventricular assist device Implant Eligibility with Non-invasive Assessment: the SIENA protocol
Matteo Cameli, Ferdinando Loiacono*, Stefania Sparla, Marco Solari, Elisabetta Iardino, Giulia Elena Mandoli, Sonia Bernazzali, Massimo Maccherini, Sergio Mondillo
University of Siena Department of Cardiovascular Diseases
Corresponding Author: Ferdinando Loiacono ,Email:
Background. In patients with end-stage left ventricular heart failure who receive left ventricular assist device (LVAD) implantation, right ventricular (RV) failure represents a possible critical complication that heavily affects morbidity and mortality. Several clinical, laboratory, hemodynamic, and echocardiographic variables have been found to be associated with RV failure occurrence after surgery. Different models and risk scores have been proposed, with poor results. No accordance has ever been reached about RV pre-operative evaluation, and time has come to introduce a standardized systematic protocol for LVAD suitability assessment according to RV function. Methods and Results. We analyzed imaging parameters associated with LVAD implantation-related RV failure, in order to identify the minimum number for pre-operative reliable prediction of post-operative RV failure. A few echocardiographic parameters have been identified as the most reliable, or promising, and reproducible tools in this field: free wall RV longitudinal strain, RV fractional area change, RV sphericity index, and RV ejection fraction with 3D-echocardiography. Conclusions. We propose the Systematic LVAD Implant Eligibility with Non-invasive Assessment protocol - the SIENA protocol - as a new and simple way of pre-operative evaluation of patients candidates to LVAD implantation.
Keywords: Right ventricle, Heart failure, Left ventricular assist device, Strain, Echocardiography
Volume 26, No 1
Korean Society of Journal of Cardiovascular Ultrasound Office
1215 Hyundaihyel, 173 Mapo-daero, Mapo-gu, Seoul, 04130, Korea
TEL : +82-2-3147-0930   FAX:+82-2-3147-0933   E-mail:
BrowseCurrent IssueFor Authors and ReviewersAbout
Copyright@2011 Korean Society of Journal of Cardiovascular Ultrasound Research. All right reserved.