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Diagnosis, Treatment, and Prevention of Cardiovascular Toxicity Related to Anti-Cancer Treatment in Clinical Practice: An Opinion Paper from the Working Group on Cardio-oncology of the Korean Society of Echocardiography
Hyungseop Kim1, Woo-Baek Chung2, Kyoung Im Cho3, Bong-Joon Kim3, Jeong-Sook Seo4, Seong-MI Park5, Hak Jin Kim6, Ju-Hee Lee7, Eun Kyoung Kim8, Ho-Joong Youn2*
1Keimyung University Dongsan Medical Center
2The Catholic University of Korea College of Medicine
3Kosin Univeristy College of Medicine
4Busan Paik Hospital, Inje University
5Korea University College of Medicine
6Center for Clinical Specialty, National Cancer Center
7Chungbuk National University College of Medicine
8Sungkyunkwan University School of Medicine
Corresponding Author: Ho-Joong Youn ,Email:
Cardiovascular toxicity associated with anti-cancer treatment is commonly encountered and raises critical problems that often result in serious morbidity or mortality. Most cardiac toxicities are related to the cumulative dose of chemotherapy; however, the type of chemotherapy, concomitant agents, and/or conventional cardiovascular risk factors have been frequently implicated in cardiovascular toxicity. Approximately half of the patients exhibiting cardiovascular toxicity receive an anthracycline-based regimen. Therefore, serologic biomarkers or cardiac imaging is important during anti-cancer treatment for early detection and the decision of appropriate management of cardiotoxicity. However, given the difficulty in determining a causal relationship, a multidisciplinary collaborative approach between cardiologists and oncologists is required. In this review, we summarize the cardiovascular toxicity and focus on the role of cardiac imaging in management strategies for cardiotoxicity associated with anti-cancer treatment.
Keywords: Cardiovascular toxcity, Cardio-oncology, Anti-cancer treatment
Volume 26, No 1
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